NCBI and Uniprot Product Information
Uniprot Description
SRF: a transcription factor of the MADS domain family that binds to the serum response element (SRE). Regulates the transcription of immediate early genes including c-fos. Binds DNA as a multimer, probably a dimer.
Protein type: Transcription factor; Motility/polarity/chemotaxis
Cellular Component: cell; cytoplasm; nuclear chromatin; nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein dimerization activity; protein binding; protein homodimerization activity; DNA binding; chromatin DNA binding; sequence-specific DNA binding; histone deacetylase binding; chromatin binding; transcription factor binding; transcription factor activity
Biological Process: developmental growth; positive regulation of transcription, DNA-dependent; positive regulation of axon extension; heart development; multicellular organismal development; gastrulation; muscle maintenance; cell-cell adhesion; tangential migration from the subventricular zone to the olfactory bulb; morphogenesis of an epithelial sheet; neurite development; platelet activation; skin morphogenesis; transcription, DNA-dependent; leukocyte differentiation; actin filament organization; trophectodermal cell differentiation; patterning of blood vessels; regulation of water loss via skin; cell migration during sprouting angiogenesis; mesoderm formation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of cell differentiation; actin cytoskeleton organization and biogenesis; transcription from RNA polymerase II promoter; erythrocyte development; positive regulation of transcription by glucose; cell-matrix adhesion; response to hormone stimulus; neuron migration; cardiac myofibril assembly; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; positive regulation of smooth muscle contraction; heart looping; negative regulation of cell migration; associative learning; positive thymic T cell selection; regulation of cell adhesion; positive regulation of filopodium formation; in utero embryonic development; hippocampus development; sarcomere organization; mRNA transcription from RNA polymerase II promoter; contractile actin filament bundle formation; long-term memory; response to cytokine stimulus; stress fiber formation; platelet formation
Research Articles on Srf
Similar Products
Product Notes
The Rat Srf srf (Catalog #AAA3809854) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3809854 ELISA Kit recognizes Rat Srf. It is sometimes possible for the material contained within the vial of "Serum Response Factor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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