Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Protein max (MAX) Standard Curve.)
Rat Protein Max (MAX) ELISA Kit | MAX elisa kit
Rat Protein Max (MAX) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Protein max (MAX) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Protein max (MAX) Standard Curve.)
Background: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Unlike MYC, the steady state level of MAX RNA was not significantly modulated with respect to proliferation or differentiation. Unlike MYC RNA, MAX RNA was relatively stable with a half-life of more than 3 hours, and therefore it did not exhibit the characteristic short half-life of RNAs encoded by most immediate early genes.
NCBI and Uniprot Product Information
NCBI Description
human homolog is a transcriptional regulator that binds Myc [RGD, Feb 2006]
Uniprot Description
MAX: a transcription factor. Forms a DNA- binding protein complex with MYC or MAD. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. CPG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC/MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3-K9 histone methyltransferase activity. Three alternatively spliced isoforms have been reported.
Protein type: Transcription factor; DNA-binding
Cellular Component: cytoplasm; dendrite; nucleoplasm; nucleus; PML body
Molecular Function: DNA binding; protein binding; protein complex binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; transcription factor activity
Biological Process: cellular response to starvation; neuron apoptosis; protein complex assembly; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to axon injury; response to insulin stimulus; response to organic nitrogen; retina development in camera-type eye; transcription, DNA-dependent
Research Articles on MAX
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Product Notes
The Rat MAX max (Catalog #AAA9712315) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9712315 ELISA Kit recognizes Rat MAX. It is sometimes possible for the material contained within the vial of "Protein Max (MAX), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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