Rat Gastrin Releasing Peptide (GRP) ELISA Kit | GRP elisa kit

Rat Gastrin Releasing Peptide (GRP) ELISA Kit

Cat. Num. AAA3808369

• Gene Names: GRP; BN; GRP-10; proGRP; preproGRP
• Reactivity: Rat
• Synonyms: Gastrin Releasing Peptide (GRP); Rat Gastrin Releasing Peptide (GRP) ELISA Kit; GRP elisa kit

• Reactivity: Rat
• Sequence Length: 141

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 3 pg/ml-48 pg/ml
• Sensitivity: 0.1 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for GRP elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofGRP in the sample, This GRPKit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusGRP concentration. The concentration ofGRP in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 60498997
• NCBI GeneID: 2922
• NCBI Accession #: NP_001012530.1
• NCBI GenBank Nucleotide #: NP_001012530.1
• UniProt Accession #: P07492
• NCBI Official Full Name: gastrin-releasing peptide isoform 2
• NCBI Official Synonym Full Names: gastrin releasing peptide
• NCBI Official Symbol: GRP
• NCBI Official Synonym Symbols: BN; GRP-10; proGRP; preproGRP
• NCBI Protein Information: gastrin-releasing peptide
• UniProt Protein Name: Gastrin-releasing peptide
• Protein Family: Gastrin-releasing peptide
• UniProt Gene Name: GRP
• UniProt Synonym Gene Names: GRP
• UniProt Entry Name: GRP_HUMAN

NCBI Description

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

GRP: GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear. Belongs to the bombesin/neuromedin-B/ranatensin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 18q21.1-q21.32

Cellular Component: extracellular space; extracellular region

Molecular Function: neuropeptide hormone activity; receptor binding

Biological Process: neuropeptide signaling pathway; signal transduction