Rat Fibrinogen Gamma (FGg) ELISA Kit | FGg elisa kit
Rat Fibrinogen Gamma (FGg) Mini Samples ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
combines with alpha and beta polypeptides to form the mature fibrinogen molecule; plays a role in inflammatory response [RGD, Feb 2006]
Uniprot Description
FGG: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. Defects in FGG are a cause of congenital afibrinogenemia (CAFBN). This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen. Patients with congenital fibrinogen abnormalities can manifest different clinical pictures. Some cases are clinically silent, some show a tendency toward bleeding and some show a predisposition for thrombosis with or without bleeding. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 2q34
Cellular Component: cell cortex; cell surface; cytoplasm; external side of plasma membrane; extracellular space; fibrinogen complex
Molecular Function: cell adhesion molecule binding; protein homodimerization activity; receptor binding; structural molecule activity
Biological Process: cell-matrix adhesion; cellular protein complex assembly; fibrinolysis; plasminogen activation; positive regulation of exocytosis; positive regulation of heterotypic cell-cell adhesion; positive regulation of protein secretion; positive regulation of vasoconstriction; protein polymerization; protein secretion; response to calcium ion
Research Articles on FGg
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Product Notes
The Rat FGg fgg (Catalog #AAA2088002) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2088002 ELISA Kit recognizes Rat FGg. It is sometimes possible for the material contained within the vial of "Fibrinogen Gamma (FGg), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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