Rat F-box/WD repeat-containing protein 10 (FBXW10) ELISA Kit | FBXW10 elisa kit
Rat F-box/WD repeat-containing protein 10 (FBXW10) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Uniprot Description
FBXW10: Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17p12
Research Articles on FBXW10
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Product Notes
The Rat FBXW10 fbxw10 (Catalog #AAA7219879) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7219879 ELISA Kit recognizes Rat FBXW10. It is sometimes possible for the material contained within the vial of "F-box/WD repeat-containing protein 10 (FBXW10), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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