Rat Coronin-1A (Coro1a/Coro1) ELISA Kit | Coro1a/Coro1 elisa kit
Rat Coronin-1A, Coro1a/Coro1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
actin binding protein; human homolog may be a component of the cytoskeleton and may be involved in mitosis [RGD, Feb 2006]
Uniprot Description
coronin 1A: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. Belongs to the WD repeat coronin family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Cellular Component: cortical actin cytoskeleton; protein complex; cell; leading edge; early endosome; immunological synapse; actin filament; phagocytic vesicle; intercellular junction; actin cytoskeleton; phagocytic vesicle membrane; membrane; axon; lamellipodium; cytoplasm; plasma membrane; intracellular; nucleus; phagocytic cup
Molecular Function: protein C-terminus binding; actin filament binding; identical protein binding; protein homodimerization activity; cytoskeletal protein binding; phosphoinositide 3-kinase binding
Biological Process: cell migration; negative regulation of vesicle fusion; leukocyte chemotaxis; regulation of actin polymerization and/or depolymerization; actin filament organization; phagocytosis; cell-substrate adhesion; regulation of release of sequestered calcium ion into cytosol; uropod organization and biogenesis; phagolysosome formation; regulation of cell shape; regulation of actin filament polymerization; positive chemotaxis; homeostasis of number of cells within a tissue; response to cytokine stimulus; negative regulation of actin nucleation; calcium ion transport; positive regulation of T cell proliferation; T cell homeostasis; negative regulation of neuron apoptosis; positive regulation of T cell activation; actin cytoskeleton organization and biogenesis; T cell differentiation; positive regulation of cell migration
Research Articles on Coro1a/Coro1
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Product Notes
The Rat Coro1a/Coro1 coro1a (Catalog #AAA9329748) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329748 ELISA Kit recognizes Rat Coro1a/Coro1. It is sometimes possible for the material contained within the vial of "Coronin-1A (Coro1a/Coro1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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