Rat Amyloid beta A4 precursor protein-binding family A member 2 (APBA2) ELISA Kit | APBA2 elisa kit

Rat Amyloid beta A4 precursor protein-binding family A member 2 (APBA2) ELISA Kit

Cat. Num. AAA7241471

• Gene Names: Apba2; Mint2
• Reactivity: Rat
• Synonyms: Amyloid beta A4 precursor protein-binding family A member 2 (APBA2); Rat Amyloid beta A4 precursor protein-binding family A member 2 (APBA2) ELISA Kit; APBA2 elisa kit

• Reactivity: Rat

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Assay Type: Competitive
• Detection Range: 1.0-25ng/mL
• Sensitivity: 0.1ng/ml
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for APBA2 elisa kit

Neurobiology

NCBI and Uniprot Product Information

• NCBI GI #: 13929102
• NCBI GeneID: 83610
• NCBI Accession #: NP_113968.1
• NCBI GenBank Nucleotide #: NM_031780.1
• Molecular Weight: 82,850 Da
• NCBI Official Full Name: amyloid beta A4 protein-binding family A member 2
• NCBI Official Synonym Full Names: amyloid beta (A4) precursor protein-binding, family A, member 2
• NCBI Official Symbol: Apba2
• NCBI Official Synonym Symbols: Mint2
• NCBI Protein Information: amyloid beta A4 precursor protein-binding family A member 2; mint-2; adapter protein X11beta; neuron-specific X11L protein; neuronal Munc18-1-interacting protein 2; amyloid beta (A4) precursor protein-binding family A member 2 (X11-like); amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
• UniProt Protein Name: Amyloid beta A4 precursor protein-binding family A member 2
• Protein Family: Amyloid beta A4 precursor protein-binding family
• UniProt Gene Name: Apba2
• UniProt Synonym Gene Names: Mint2; Mint-2
• UniProt Entry Name: APBA2_RAT

NCBI Description

component of multimeric complex containing component of multimeric complex containing Munc18-1 and syntaxin; binds PIP and PIP2; may mediate synaptic vesicle docking/fusion [RGD, Feb 2006]

Uniprot Description

APBA2: Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. Part of a multimeric complex containing STXBP1 and syntaxin-1. Binds to the cytoplasmic domain of amyloid protein beta, and to the nuclear factor NF-kappa-B/p65 via its PDZ domain. Interacts with the N-terminal domain of APBA2BP. Brain.

Protein type: Adaptor/scaffold

Cellular Component: plasma membrane

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding; beta-amyloid binding

Biological Process: synaptic transmission; synaptic vesicle exocytosis; protein transport; regulation of gene expression; in utero embryonic development; multicellular organism growth; locomotory behavior