NCBI Description
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]
Uniprot Description
ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q32
Cellular Component: extracellular region; extracellular space
Molecular Function: protein binding
Biological Process: inflammatory response; negative regulation of interleukin-6 production; negative regulation of tumor necrosis factor production; platelet degranulation
Product Notes
The Rat a1AGP orm1 (Catalog #
AAA2088828) is a DIY ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2088828 DIY ELISA Kit recognizes Rat a1AGP. Main materials for "Do It Yourself ELISA Kit". Researchers should empirically determine the suitability of the a1AGP orm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"Alpha-1-Acid Glycoprotein (a1AGP), DIY ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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purchaser may be intending to use a product outside of our accepted criteria.
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