Prolactin Active Protein | PRL active protein

Purified recombinant Rat Prolactin protein

Cat. Num. AAA5308892

• Gene Names: PRL; GHA1
• Purity: > 95% pure; Purified using a proprietary chromatographic technique.
• Synonyms: Prolactin; Purified recombinant Rat Prolactin protein; Prolactin protein; PRL active protein

• Host: Rat
• Purity/Purification: > 95% pure; Purified using a proprietary chromatographic technique.
• Form/Format: Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 8.0 + 50 mM NaCl
• Sequence Length: 227

• Expression: E Coli
• Bioactivity: The ED50 determined by the dose-dependent stimulation of the proliferation of rat lymphoma, Nb2-11 cells was found to be in the range of 0.01-10 ng/ml
• Preparation and Storage: Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

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Product Categories/Family for PRL active protein

Hormones & Steroids

NCBI and Uniprot Product Information

• NCBI GI #: 254675133
• NCBI GeneID: 5617
• NCBI Accession #: NP_001157030.1
• NCBI GenBank Nucleotide #: NM_001163558.2
• UniProt Accession #: P01236; Q15199; Q92996
• Molecular Weight: 25,876 Da
• NCBI Official Full Name: prolactin
• NCBI Official Synonym Full Names: prolactin
• NCBI Official Symbol: PRL
• NCBI Official Synonym Symbols: GHA1
• NCBI Protein Information: prolactin
• UniProt Protein Name: Prolactin
• Protein Family: Prolactin
• UniProt Gene Name: PRL
• UniProt Synonym Gene Names: PRL

NCBI Description

This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Uniprot Description

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: extracellular region

Molecular Function: prolactin receptor binding; protein binding

Biological Process: cell proliferation; cell surface receptor linked signal transduction; cellular protein metabolic process; positive regulation of JAK-STAT cascade; regulation of multicellular organism growth