Human Ras association (RalGDS/AF-6) domain family member 2 ELISA Kit | RASSF2 elisa kit

Human Ras association domain-containing protein 2, RASSF2 ELISA Kit

Cat. Num. AAA9328280

• Gene Names: RASSF2; CENP-34; RASFADIN
• Reactivity: Human
• Synonyms: Ras association (RalGDS/AF-6) domain family member 2; Human Ras association domain-containing protein 2; RASSF2 ELISA Kit; Human Ras association domain-containing protein 2 (RASSF2) ELISA kit; DKFZp781O1747; KIAA0168; RASFADIN; Ras association (RalGDS/AF-6) domain family 2; Ras association domain family 2; RASSF2 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 7661964
• NCBI GeneID: 9770
• NCBI Accession #: NP_055552.1
• NCBI GenBank Nucleotide #: NM_014737.2
• UniProt Accession #: P50749; Q17S06; Q53HD0; Q6AHZ2; Q8IZA5; A6NIX9; A8K5Z3
• Molecular Weight: 37,790 Da
• NCBI Official Full Name: ras association domain-containing protein 2
• NCBI Official Synonym Full Names: Ras association (RalGDS/AF-6) domain family member 2
• NCBI Official Symbol: RASSF2
• NCBI Official Synonym Symbols: CENP-34; RASFADIN
• NCBI Protein Information: ras association domain-containing protein 2; centromere protein 34; Ras association (RalGDS/AF-6) domain family 2
• UniProt Protein Name: Ras association domain-containing protein 2
• Protein Family: Ras association domain-containing protein
• UniProt Gene Name: RASSF2
• UniProt Synonym Gene Names: KIAA0168
• UniProt Entry Name: RASF2_HUMAN

NCBI Description

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

RASSF2: Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.

Protein type: Cell cycle regulation; Tumor suppressor

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: ossification; regulation of osteoclast differentiation; regulation of osteoblast differentiation; homeostasis of number of cells; cell cycle; bone remodeling; skeletal development