Mouse Rap guanine nucleotide exchange factor (GEF) 3 ELISA Kit | RAPGEF3 elisa kit

Mouse Rap guanine nucleotide exchange factor 3, RAPGEF3 ELISA Kit

Cat. Num. AAA9329634

• Gene Names: Rapgef3; Epac; Epac1; 2310016P22Rik; 9330170P05Rik
• Reactivity: Mouse
• Synonyms: Rap guanine nucleotide exchange factor (GEF) 3; Mouse Rap guanine nucleotide exchange factor 3; RAPGEF3 ELISA Kit; Mouse Rap guanine nucleotide exchange factor 3 (RAPGEF3) ELISA kit; CAMP-GEFI; EPAC; EPAC1; HSU79275; MGC21410; bcm910; 9330170P05Rik; Rap guanine nucleotide exchange factor 3; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; exchange protein directl; RAPGEF3 elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Human Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for RAPGEF3 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of RAP3A (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 295317405
• NCBI GeneID: 223864
• NCBI Accession #: NP_001171281.1
• NCBI GenBank Nucleotide #: NM_001177810.1
• UniProt Accession #: Q8VCC8; Q8BZK9; Q8R1R1
• Molecular Weight: 103,533 Da
• NCBI Official Full Name: rap guanine nucleotide exchange factor 3 isoform 1
• NCBI Official Synonym Full Names: Rap guanine nucleotide exchange factor (GEF) 3
• NCBI Official Symbol: Rapgef3
• NCBI Official Synonym Symbols: Epac; Epac1; 2310016P22Rik; 9330170P05Rik
• NCBI Protein Information: rap guanine nucleotide exchange factor 3; cAMP-GEFI; exchange protein directly activated by cAMP 1; cAMP-regulated guanine nucleotide exchange factor I; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP
• UniProt Protein Name: Rap guanine nucleotide exchange factor 3
• Protein Family: Rap guanine nucleotide exchange factor
• UniProt Gene Name: Rapgef3
• UniProt Synonym Gene Names: Epac; Epac1; EPAC 1; cAMP-GEFI
• UniProt Entry Name: RPGF3_MOUSE

Uniprot Description

Epac1: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, misc.

Cellular Component: membrane; cytoplasm; intracellular; cAMP-dependent protein kinase complex

Molecular Function: Rap guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; nucleotide binding; cAMP-dependent protein kinase regulator activity; cAMP binding

Biological Process: positive regulation of syncytium formation by plasma membrane fusion; positive regulation of protein export from nucleus; regulation of small GTPase mediated signal transduction; positive regulation of angiogenesis; regulation of protein amino acid phosphorylation; small GTPase mediated signal transduction; positive regulation of stress fiber formation; angiogenesis; positive regulation of peptidyl-serine phosphorylation; Rap protein signal transduction; positive regulation of GTPase activity