Mouse RAD51-like 3 (S. cerevisiae) ELISA Kit | RAD51L3 elisa kit
Mouse DNA repair protein RAD51 homolog 4, RAD51L3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the Rad51 gene family whose products play a major role in homologous recombination and DNA repair. The encoded protein interacts with other proteins of this family, including Rad51b, Rad51c and Xrcc2, and plays an essential role in both DNA repair and telomere maintenance. In humans, germline mutations in this gene may be associated with predisposition to ovarian cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Uniprot Description
RAD51L3: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Defects in RAD51D are a cause of susceptibility to familial breast-ovarian cancer type 4 (BROVCA4). A condition associated with familial predisposition to cancer of the breast and ovaries. Characteristic features in affected families are an early age of onset of breast cancer (often before age 50), increased chance of bilateral cancers (cancer that develop in both breasts, or both ovaries, independently), frequent occurrence of breast cancer among men, increased incidence of tumors of other specific organs, such as the prostate. Belongs to the RecA family. RAD51 subfamily. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Cellular Component: centrosome; chromosome, telomeric region; cytoplasm; replication fork; chromosome; nucleus
Molecular Function: DNA-dependent ATPase activity; protein binding; gamma-tubulin binding; four-way junction DNA binding; DNA binding; nucleotide binding; single-stranded DNA binding; ATP binding
Biological Process: nucleotide-excision repair; regulation of cell cycle; strand invasion; DNA repair; response to DNA damage stimulus; chromosome organization and biogenesis; telomere maintenance; double-strand break repair via homologous recombination; DNA recombination
Research Articles on RAD51L3
Similar Products
Product Notes
The Mouse RAD51L3 rad51d (Catalog #AAA9335331) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335331 ELISA Kit recognizes Mouse RAD51L3. It is sometimes possible for the material contained within the vial of "RAD51-like 3 (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
