Putative DNA repair protein RAD23-2 (RAD23-2) Recombinant Protein | RAD23-2 recombinant protein
Recombinant Arabidopsis thaliana Putative DNA repair protein RAD23-2 (RAD23-2)
NCBI and Uniprot Product Information
NCBI Description
Encodes a member of the RADIATION SENSITIVE23 (RAD23) family: AT1G16190(RAD23A), AT1G79650(RAD23B), AT3G02540(RAD23C), AT5G38470(RAD23D). RAD23 proteins play an essential role in the cell cycle, morphology, and fertility of plants through their delivery of UPS (ubiquitin/26S proteasome system) substrates to the 26S proteasome.
Uniprot Description
May be involved in nucleotide excision repair (). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP) ().