Immunohistochemistry
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ADRA1D antibody.)
Rabbit ADRA1D Antibody | anti-ADRA1D antibody
ADRA1D Antibody
IF: 1:100~1:500
ELISA: 1:40000
Immunohistochemistry
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ADRA1D antibody.)
Immunohistochemistry
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ADRA1D antibody.)
Immunofluorescence
(Immunofluorescence analysis of HeLa cells, using ADRA1D antibody.)
Immunofluorescence
(Immunofluorescence analysis of HeLa cells, using ADRA1D antibody.)
NCBI and Uniprot Product Information
NCBI Description
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]
Uniprot Description
ADRA1D: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding
Biological Process: cell proliferation; cell-cell signaling; DNA metabolic process; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); multicellular organismal development; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; positive regulation of cell proliferation; positive regulation of smooth muscle contraction; positive regulation of vasoconstriction
Research Articles on ADRA1D
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Product Notes
The ADRA1D adra1d (Catalog #AAA9383436) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADRA1D Antibody reacts with Human (Identities = 100%, Positives = 100%) and may cross-react with other species as described in the data sheet. AAA Biotech's ADRA1D can be used in a range of immunoassay formats including, but not limited to, IHC, IF, ELISA. IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:40000. Researchers should empirically determine the suitability of the ADRA1D adra1d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADRA1D, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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