Typical Testing Data/Standard Curve (for reference only)
Rabbit FRS3 ELISA Kit | FRS3 elisa kit
Rabbit FRS3 (Fibroblast Growth Factor Receptor Substrate 3) ELISA Kit
Gene Names
FRS3; SNT2; FRS2B; SNT-2; FRS2beta; FRS2-beta
Reactivity
Rabbit
Synonyms
FRS3; Rabbit FRS3 (Fibroblast Growth Factor Receptor Substrate 3) ELISA Kit; FRS3 elisa kit
Reactivity
Rabbit
Specificity
This kit recognizes natural and recombinant Rabbit FRS3. No significant cross-reactivity or interference between Rabbit FRS3 and analogues was observed.
Sequence Length
492
Samples
Serum, Plasma, Biological Fluids
Assay Type
Sandwich
Detection Range
1.563-100ng/mL
Sensitivity
Min: 0.938ng/mL; Max: 100ng/mL
Preparation and Storage
Store at 4 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for FRS3 elisa kit
Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rabbit FRS3 concentrations in serum, plasma and other biological fluids.
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to FRS3. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for FRS3 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain FRS3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of FRS3. You can calculate the concentration of FRS3 in the samples by comparing the OD of the samples to the standard curve.
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to FRS3. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for FRS3 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain FRS3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of FRS3. You can calculate the concentration of FRS3 in the samples by comparing the OD of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,462 Da
NCBI Official Full Name
fibroblast growth factor receptor substrate 3
NCBI Official Synonym Full Names
fibroblast growth factor receptor substrate 3
NCBI Official Symbol
FRS3
NCBI Official Synonym Symbols
SNT2; FRS2B; SNT-2; FRS2beta; FRS2-beta
NCBI Protein Information
fibroblast growth factor receptor substrate 3; FGFR substrate 3; FGFR-signaling adaptor SNT2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor)
UniProt Protein Name
Fibroblast growth factor receptor substrate 3
Protein Family
UniProt Gene Name
FRS3
UniProt Synonym Gene Names
FGFR substrate 3; SNT-2
UniProt Entry Name
FRS3_HUMAN
NCBI Description
This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013]
Uniprot Description
FRS3: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: plasma membrane
Molecular Function: protein binding; insulin receptor binding; fibroblast growth factor receptor binding
Biological Process: fibroblast growth factor receptor signaling pathway; signal transduction
Research Articles on FRS3
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Product Notes
The Rabbit FRS3 frs3 (Catalog #AAA2506670) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2506670 ELISA Kit recognizes Rabbit FRS3. It is sometimes possible for the material contained within the vial of "FRS3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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