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Rabbit Cytokine-dependent hematopoietic cell linker (CLNK) ELISA Kit | CLNK elisa kit

Rabbit Cytokine-dependent hematopoietic cell linker (CLNK) ELISA Kit

Gene Names
CLNK; MIST
Reactivity
Rabbit
Synonyms
Cytokine-dependent hematopoietic cell linker (CLNK); Rabbit Cytokine-dependent hematopoietic cell linker (CLNK) ELISA Kit; CLNK elisa kit
Ordering
For Research Use Only!
Reactivity
Rabbit
Samples
Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
Preparation and Storage
Store all reagents at 2-8 degree C.
Product Categories/Family for CLNK elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,469 Da
NCBI Official Full Name
cytokine-dependent hematopoietic cell linker
NCBI Official Synonym Full Names
cytokine-dependent hematopoietic cell linker
NCBI Official Symbol
CLNK
NCBI Official Synonym Symbols
MIST
NCBI Protein Information
cytokine-dependent hematopoietic cell linker; mast cell immunoreceptor signal transducer
UniProt Protein Name
Cytokine-dependent hematopoietic cell linker
UniProt Gene Name
CLNK
UniProt Synonym Gene Names
MIST
UniProt Entry Name
CLNK_HUMAN

NCBI Description

MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]

Uniprot Description

MIST: Plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation. Involved in phosphorylation of LAT. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: intracellular

Molecular Function: protein binding; SH3/SH2 adaptor activity

Biological Process: positive regulation of signal transduction; immune response; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on CLNK

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Product Notes

The Rabbit CLNK clnk (Catalog #AAA7240281) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7240281 ELISA Kit recognizes Rabbit CLNK. It is sometimes possible for the material contained within the vial of "Cytokine-dependent hematopoietic cell linker (CLNK), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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