Rabbit WWOX Antibody
Anti-WWOX Antibody
Applications
Immunoblot, Western Blot
Synonyms
WWOX; Anti-WWOX Antibody; WWOX Antibody; anti-WWOX antibody
Host
Rabbit
Specificity
WWOX Antibody [Human and mouse WWOX]
This antibody recognizes human and mouse WWOX. Sequence identity to chimpanzee and orangutan WWOX is 100%.
This antibody recognizes human and mouse WWOX. Sequence identity to chimpanzee and orangutan WWOX is 100%.
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-WWOX antibody
Immunoblot
Application Notes
Immunoblotting : use at 1:5,000 dilution. A band of approximately 46 kDa is detected.
Positive control: MCF-7 human breast cancer cell lysate or murine fibroblast L929 cell lysate.
Positive control: MCF-7 human breast cancer cell lysate or murine fibroblast L929 cell lysate.
Immunogen
Synthetic peptide corresponding to amino acids 89-107 (RLAFTVDDNPTKPTTRQRY) of human WWOX conjugated to KLH at the C-terminus.
Stabilizer
None
Preservatives
None. Available on request.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-WWOX antibody
WW domain-containing oxidoreductase, WWOX, also known as WOX1 or FOR, is a proapoptotic protein expressed by a tumor suppressor gene. Because mutation or deletion in the coding region of WWOX is rarely found, it is speculated that the appearance of aberrant transcripts affects progression of many cancers. In addition, protein levels of WWOX, its Tyr33-phosphorylated form, and WOX2 are significantly down-regulated in the neurons of Alzheimer's hippocampi.
Product Categories/Family for anti-WWOX antibody
References
Chang, N.S et al. Oncogene (2005) 24: 714-723.
Aqeilan, R.I. et al. Cancer Res (2004) 64: 8256-8261.
Sze, C.I. et al. J Biol Chem (2004) 279: 30498-30506.
Aqeilan, R.I. et al. Cancer Res (2004) 64: 8256-8261.
Sze, C.I. et al. J Biol Chem (2004) 279: 30498-30506.
Similar Products
Product Notes
The WWOX (Catalog #AAA194150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's WWOX can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting : use at 1:5,000 dilution. A band of approximately 46 kDa is detected. Positive control: MCF-7 human breast cancer cell lysate or murine fibroblast L929 cell lysate. Researchers should empirically determine the suitability of the WWOX for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WWOX, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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