Rabbit GPR15 (NT) Antibody | anti-GPR15 antibody
Anti-GPR15/BOB Antibody
Gene Names
GPR15; MGC126828; MGC126830
Applications
Immunoblot, Western Blot
Synonyms
GPR15 (NT); Anti-GPR15/BOB Antibody; Anti-GPR15 (NT); HIV Co-Receptor GPR15/BOB; anti-GPR15 antibody
Host
Rabbit
Specificity
Anti-GPR15 (NT) [Rabbit antibody to peptide corresponding to aa 13-28 of human GRP15. This sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid.]
This antibody recognizes GPR15/BOB of human, mouse, and rat (50 kD).
This antibody recognizes GPR15/BOB of human, mouse, and rat (50 kD).
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-GPR15 antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:2,000 dilution.
Positive control: Jurkat or A549 cell lysate.
Positive control: Jurkat or A549 cell lysate.
Antigen
Peptide corresponding to aa 13- 28 of human GPR15. This sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-GPR15 antibody
Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1, and V28 have been recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G proteincoupled receptor 15 and brother of Bonzo) have been cloned. This novel g proteincoupled receptor serves as co-receptor for SIV and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 is under investigation.
Product Categories/Family for anti-GPR15 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,787 Da
NCBI Official Full Name
G-protein coupled receptor 15
NCBI Official Synonym Full Names
G protein-coupled receptor 15
NCBI Official Symbol
GPR15
NCBI Official Synonym Symbols
MGC126828; MGC126830
NCBI Protein Information
G-protein coupled receptor 15; BOB; brother of Bonzo; OTTHUMP00000217372
UniProt Protein Name
G-protein coupled receptor 15
Protein Family
UniProt Gene Name
GPR15
UniProt Entry Name
GPR15_HUMAN
NCBI Description
This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]
Uniprot Description
GPR15: Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1
Chromosomal Location of Human Ortholog: 3q11.2-q13.1
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on GPR15
Similar Products
Product Notes
The GPR15 gpr15 (Catalog #AAA194095) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GPR15 (NT) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:2,000 dilution. Positive control: Jurkat or A549 cell lysate. Researchers should empirically determine the suitability of the GPR15 gpr15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR15 (NT), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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