RAB24 recombinant protein
Recombinant Human RAB24, Member RAS Oncogene Family
Sterile Filtered colorless solution.
Introduction: RAB24 is a member of the small GTPase superfamily which regulates intracellular protein transferring, nonetheless the specific role of RAB24 has not yet been revealed. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures which suggests connection to autophagy-related courses. RAB24 demonstrates uncommon characteristics such as low intrinsic GTPase activity, and is incompetently prenylated when compared with other Rab proteins indicates that RAB24 has a distinctive part in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope.
NCBI and Uniprot Product Information
NCBI Description
RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]
Uniprot Description
RAB24: a small G protein of the Rab family. Differs from other Rab proteins in that it has a low intrinsic GTPase activity. May be involved in autophagy-related processes.
Protein type: Autophagy; G protein, monomeric; G protein; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: mitochondrion; membrane; endocytic vesicle; autophagic vacuole; cytosol; endosome
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding
Biological Process: intracellular protein transport; autophagy; Rab protein signal transduction
Research Articles on RAB24
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Product Notes
The RAB24 rab24 (Catalog #AAA144834) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSHMS GQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH. It is sometimes possible for the material contained within the vial of "RAB24, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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