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Pentraxin-related protein PTX3 Recombinant Protein | PTX3 recombinant protein
Recombinant Mouse Pentraxin-related protein PTX3 (N-6His)
Gene Names
Ptx3; TSG-14; AI607804
Purity
>90% as determined by reducing SDS-PAGE
Synonyms
Pentraxin-related protein PTX3; Recombinant Mouse Pentraxin-related protein PTX3 (N-6His); alpha-induced protein 5; pentaxin-related gene; rapidly induced by IL-1 beta; tumor necrosis factor; Pentaxin-related protein PTX3; Pentraxin 3; pentraxin 3; long; pentraxin-3; pentraxin-related gene; pentraxin-related protein PTX3; PTX3; TNF alpha-induced protein 5; TNFAIP5; TSG14; TSG-14; PTX3 recombinant protein
Host
Human Cells
Purity/Purification
>90% as determined by reducing SDS-PAGE
Form/Format
Supplied as a 0.2um filtered solution of PBS, pH7.4.
Sequence
His18-Ser381
Species
Mouse
Tag
N-6His
Endotoxin
<1.0EU per ug as determined by the LAL method.
Protein Construction
Recombinant Mouse Pentraxin-related protein PTX3 is produced by our Mammalian expression system and the target gene encoding His18-Ser381 is expressed with a 6His tag at the N-terminus.
Preparation and Storage
Store at < -20 degree C, stable for 6 months. Please minimize freeze-thaw cycles.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20 degree C.
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20 degree C.
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Related Product Information for PTX3 recombinant protein
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It's subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
41,812 Da
NCBI Official Full Name
Pentraxin-related protein PTX3
NCBI Official Synonym Full Names
pentraxin related gene
NCBI Official Symbol
Ptx3
NCBI Official Synonym Symbols
TSG-14; AI607804
NCBI Protein Information
pentraxin-related protein PTX3; pentraxin 3; pentaxin related; pentaxin-related protein PTX3; tumor necrosis factor-inducible gene 14 protein
UniProt Protein Name
Pentraxin-related protein PTX3
Protein Family
UniProt Gene Name
Ptx3
UniProt Synonym Gene Names
Tsg14; TSG-14
UniProt Entry Name
PTX3_MOUSE
Uniprot Description
PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: complement component C1q binding; zymosan binding; virion binding
Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization
Research Articles on PTX3
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Product Notes
The PTX3 ptx3 (Catalog #AAA2569368) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: His18-Ser3 81. It is sometimes possible for the material contained within the vial of "Pentraxin-related protein PTX3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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