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Putative transcriptional regulatory protein ptsJ (ptsJ) Recombinant Protein | ptsJ recombinant protein

Recombinant Salmonella typhimurium Putative transcriptional regulatory protein ptsJ (ptsJ)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Putative transcriptional regulatory protein ptsJ (ptsJ); Recombinant Salmonella typhimurium Putative transcriptional regulatory protein ptsJ (ptsJ); ptsJ recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-430, Full length protein
Sequence
MIDGKTANEIFDSIRQHIIAGTLRAEDSLPPVRELASELKVNRNTVAAAYKRLITAGLAQSLGRNGTVIKGSPSPVALEGGDPHTPLHDLSGGNPDPQRLPDLSRYFARLSRTPHLYGDAPVSPELHAWAARWLRDATPVAGEIDITSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDSEGMQPEKLERALNQGARAVILTPRAHNPTGCSLSARRAAALQNMLARYPQVVVIIDDHFALLSSSPWQPVIAQTTQHWAVIRSVSKTLGPDLRLAIVASDSATSAKLRLRLNAGSQWVSHLLQDLVYACLTDPEYQHRLTQTRLFYAARQQKLARALQQYGIAISPGDGVNAWLPLDTHSQATAFTLAKSGWLVREGEAFGVSAPSHGLRITLSTLNDSEINTLAADIHQALNR
Sequence Length
430
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,508 Da
NCBI Official Full Name
transcriptional regulator PtsJ
NCBI Official Symbol
ptsJ
NCBI Protein Information
transcriptional regulator PtsJ
UniProt Protein Name
Vitamin B6 salvage pathway transcriptional repressor PtsJ
UniProt Gene Name
ptsJ

Uniprot Description

Acts as transcriptional repressor of the pdxK gene, encoding a pyridoxal kinase involved in the vitamin B6 salvage pathway. Also represses transcription of its own gene. Binds to the ptsJ-pdxK intergenic region, but does not bind pdxY and pdxH promoters. Among all six B6 vitamers, only pyridoxal 5'-phosphate (PLP) clearly binds to the protein and acts as an effector molecule for PtsJ, inducing a protein conformational change that increases affinity for DNA. Thus, PLP stabilizes protein-DNA interactions, reinforcing repression.

Research Articles on ptsJ

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Product Notes

The ptsJ ptsj (Catalog #AAA1074086) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-430, Full length protein. The amino acid sequence is listed below: MIDGKTANEI FDSIRQHIIA GTLRAEDSLP PVRELASELK VNRNTVAAAY KRLITAGLAQ SLGRNGTVIK GSPSPVALEG GDPHTPLHDL SGGNPDPQRL PDLSRYFARL SRTPHLYGDA PVSPELHAWA ARWLRDATPV AGEIDITSGA IDAIERLLCA HLLPGDSVAV EDPCFLSSIN MLRYAGFSAS PVSVDSEGMQ PEKLERALNQ GARAVILTPR AHNPTGCSLS ARRAAALQNM LARYPQVVVI IDDHFALLSS SPWQPVIAQT TQHWAVIRSV SKTLGPDLRL AIVASDSATS AKLRLRLNAG SQWVSHLLQD LVYACLTDPE YQHRLTQTRL FYAARQQKLA RALQQYGIAI SPGDGVNAWL PLDTHSQATA FTLAKSGWLV REGEAFGVSA PSHGLRITLS TLNDSEINTL AADIHQALNR. It is sometimes possible for the material contained within the vial of "Putative transcriptional regulatory protein ptsJ (ptsJ), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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