Phosphotidylinositol phosphatase PTPRQ (Ptprq) Recombinant Protein | Ptprq recombinant protein

Recombinant Rat Phosphotidylinositol phosphatase PTPRQ (Ptprq) , partial

• Gene Names: Ptprq; rPTP-GMC1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Phosphotidylinositol phosphatase PTPRQ (Ptprq); Recombinant Rat Phosphotidylinositol phosphatase PTPRQ (Ptprq); partial; Ptprq recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 2,302

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 12621078
• NCBI GeneID: 360417
• NCBI Accession #: NP_075214.1
• NCBI GenBank Nucleotide #: NM_022925.1
• UniProt Accession #: O88488
• Molecular Weight: 256,824 Da
• NCBI Official Full Name: phosphatidylinositol phosphatase PTPRQ
• NCBI Official Synonym Full Names: protein tyrosine phosphatase, receptor type, Q
• NCBI Official Symbol: Ptprq
• NCBI Official Synonym Symbols: rPTP-GMC1
• NCBI Protein Information: phosphatidylinositol phosphatase PTPRQ
• UniProt Protein Name: Phosphatidylinositol phosphatase PTPRQ
• Protein Family: Phosphatidylinositol phosphatase
• UniProt Gene Name: Ptprq
• UniProt Synonym Gene Names: Ptpgmc1; rPTP-GMC1; PTP-RQ; R-PTP-Q

NCBI Description

may play a role in cell adhesion and migration [RGD, Feb 2006]

Uniprot Description

Phosphatidylinositol phosphatase required for auditory function. May act by regulating the level of phosphatidylinositol 4,5-bisphosphate (PIP2) level in the basal region of hair bundles. Can dephosphorylate a broad range of phosphatidylinositol phosphates, including phosphatidylinositol 3,4,5-trisphosphate and most phosphatidylinositol monophosphates and diphosphates. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by suppressing the phosphatidylinositol 3,4,5-trisphosphate (PIP3) level in MSCs and preadipocyte cells ().