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proteinase 3 / myeloblastin Blocking Peptide | PRTN3 blocking peptide

proteinase 3 / myeloblastin Immunizing Peptide

Gene Names
PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
Reactivity
Human
Synonyms
proteinase 3 / myeloblastin; proteinase 3 / myeloblastin Immunizing Peptide; PRTN3; proteinase 3; ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP4; P29; PR-3; PR3; C-ANCA antigen; NP-4; Wegener granulomatosis autoantigen; azurophil granule protein 7; leukocyte proteinase 3; myeloblastin; neutrophil proteinase 4; serine proteinase; neutrop; proteinase 3 / myeloblastin (aa88-98); PRTN3 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human
Form/Format
100ug of dried peptide
Sequence
C-HNVRTQEPTQQ
Sequence Length
256
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,807 Da
NCBI Official Full Name
myeloblastin
NCBI Official Synonym Full Names
proteinase 3
NCBI Official Symbol
PRTN3
NCBI Official Synonym Symbols
MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA
NCBI Protein Information
myeloblastin
UniProt Protein Name
Myeloblastin
Protein Family
UniProt Gene Name
PRTN3
UniProt Synonym Gene Names
MBN; PR-3; PR3; NP-4
UniProt Entry Name
PRTN3_HUMAN

Uniprot Description

PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: Cell cycle regulation; EC 3.4.21.76; Protease

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane

Molecular Function: enzyme binding; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: blood coagulation; collagen catabolic process; negative regulation of phagocytosis; positive regulation of cell proliferation; proteolysis

Research Articles on PRTN3

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Product Notes

The PRTN3 prtn3 (Catalog #AAA428493) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The proteinase 3 / myeloblastin Immunizing Peptide reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-HNVRTQEP TQQ. It is sometimes possible for the material contained within the vial of "proteinase 3 / myeloblastin, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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