PGHS - 2 protein
PGHS - 2 Peptide
Applications
Western Blot
Synonyms
PGHS - 2; PGHS - 2 Peptide; Human Prostaglandin Synthase-2 (COX-2) Synthetic Peptide; PGHS - 2 protein
Sequence Length
604
Applicable Applications for PGHS - 2 protein
Western Blot (WB)
Application Notes
Will compete with the polyclonal, anti-peptide PGHS-2 antibody in Western blotting, for confirmation of the PGHS-2 specificity of antibody binding.
Contents
100 mug of peptide in 100 muL of 0.1M ammonium bicarbonate buffer, pH 7.5.
Preparation and Storage
Stable at 4 degree C. For long term storage, aliquot product into separate tubes and freeze at At -20 degree C. Avoid repeated freeze-thaw cycles.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,163 Da
NCBI Official Full Name
prostaglandin G/H synthase 2
NCBI Official Symbol
PTGS2
NCBI Protein Information
prostaglandin G/H synthase 2; COX-2; PGH synthase 2; PGHS-2; PHS II; cyclooxygenase-2; prostaglandin H2 synthase 2
UniProt Protein Name
Prostaglandin G/H synthase 2
UniProt Gene Name
PTGS2
UniProt Synonym Gene Names
COX2; COX-2; PGH synthase 2; PGHS-2
UniProt Entry Name
PGH2_BOVIN
Uniprot Description
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis ().
Research Articles on PGHS - 2
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Product Notes
The PGHS - 2 ptgs2 (Catalog #AAA483006) is a Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PGHS - 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Will compete with the polyclonal, anti-peptide PGHS-2 antibody in Western blotting, for confirmation of the PGHS-2 specificity of antibody binding. Researchers should empirically determine the suitability of the PGHS - 2 ptgs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGHS - 2, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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