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Holo Transferrin Protein | HAN_2g338 protein

Holo Transferrin, Human Serum

Purity
>= 98% (SDS-PAGE)
Synonyms
Holo Transferrin; Human Serum; Transferrin iron-saturated; Siderophilin; TRF; Holo TnF; Transferrin; Holo; HAN_2g338 protein
Ordering
For Research Use Only!
Purity/Purification
>= 98% (SDS-PAGE)
Form/Format
Lyophilized
Sequence Length
409
Source
Human Serum
Note
Heat treated at > 58 degree C for > 10 hours.
Iron
1,200 - 1,700 ppm
EC Number
234-318-8
UNSPSC Code
51131907
Recertification
3 years
pH
6.5 - 8.0 (3% solution)
Iron Assay
1,200 - 1,700 ppm
CAS Number
11096-37-0
Preparation and Storage
2-8 degree C
Related Product Information for HAN_2g338 protein
MyBioSource is the leading supplier of Human Holo Transferrin from human serum, used for cell culture, medical research and manufacturing of clinical assays for iron deficiencies and disorders of the immune system.

Custom preparations, technical support, bulk quantities and aliquoting available.

Purification procedures include selective size exclusion, ion exchange chromatography and gel fitration for transferrin products.

Ultra Pure Human Holo Transferrin >99% pure available upon request.

Human Transferrin is a plasma protein for iron ion delivery. Human Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron binding domains. Transferrin (TF) is related to other iron binding proteins including lactoferrin. When human transferrin loaded with iron encounters a transferrin receptor on the surface of a cell, it binds to it and is consequently transported into the cell in a vesicle. The cell will acidify the vesicle, causing human transferrin(TF) to release its iron ions. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+).

Human Transferrin levels may be checked in iron deficiency, hemochromatosis and other iron overload disorders. Transferrin is also associated with the innate immune system. Human Transferrin is found in the mucosa and binds iron, thus creating an environment low in free iron, where few bacteria are able to survive.
Product Categories/Family for HAN_2g338 protein

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
77000
NCBI Official Full Name
trf
UniProt Protein Name
Trf
UniProt Gene Name
HAN_2g338
UniProt Entry Name
A9BKI4_HEMAN

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Product Notes

The Holo Transferrin han_2g338 (Catalog #AAA173195) is a Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Holo Transferrin, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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