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Protease inhibitor Hg1 Recombinant Protein

Recombinant Hadrurus gertschi Protease inhibitor Hg1

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protease inhibitor Hg1; Recombinant Hadrurus gertschi Protease inhibitor Hg1; Protease inhibitor Hg1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
22-88, Full length protein
Sequence
GHHNRVNCLLPPKTGPCKGSFARYYFDIETGSCKAFIYGGCEGNSNNFSEKHHCEKRCRGFRKFGGK
Sequence Length
67
Species
Hadrurus gertschi (Scorpion)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
9,855 Da
NCBI Official Full Name
Kunitz-type serine protease inhibitor Hg1
UniProt Protein Name
Kunitz-type serine protease inhibitor Hg1

Uniprot Description

Dual-function toxin that completely inhibits the activity of trypsin at a molar ratio of 1:1 (dissociation constant of 107 nM) and that inhibits mKv1.3/KCNA3 potassium channel currents with an IC50 of 6.2 nM (where 1 µM inhibits 80% of currents). Also has weak inhibitory activity against mKv1.1/KCNA1 (where 1 µM inhibits less than 50% of currents), hKv1.2/KCNA2 (where 1 µM inhibits less than 50% of currents), and hKCa2.3/KCNN3.

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Product Notes

The Protease inhibitor Hg1 (Catalog #AAA1012504) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-88, Full length protein. The amino acid sequence is listed below: GHHNRVNCLL PPKTGPCKGS FARYYFDIET GSCKAFIYGG CEGNSNNFSE KHHCEKRCRG FRKFGGK. It is sometimes possible for the material contained within the vial of "Protease inhibitor Hg1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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