Probable membrane protein Rv1733c/MT1774 (Rv1733c, MT1774) Recombinant Protein
Recombinant Probable membrane protein Rv1733c/MT1774 (Rv1733c, MT1774)
NCBI and Uniprot Product Information
Uniprot Description
Subcellular location: Cell membrane; Multi-pass membrane protein
Potential.
Induction: A member of the dormancy regulon. Induced in response to reduced oxygen tension (hypoxia), low levels of nitric oxide (NO) and carbon monoxide (CO). It is hoped that this regulon will give insight into the latent, or dormant phase of infection. Ref.3 Ref.4 Ref.6 Ref.7
Biotechnological use: Has strong T-cell and IFN-gamma inducing capacity in human tuberculin skin test positive patients, indicating this might be a good vaccine candidate. Has also been seen to serve as an immunogenic antigen, inducing gamma-interferon responses in whole-blood cultures from M.tuberculosis-exposed adults in Uganda, The Gambia and South Africa, also indicating this might be a good vaccine candidate. Ref.5 Ref.8
Sequence caution: The sequence AAK46047.1 differs from that shown. Reason: Erroneous initiation.
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Product Notes
The Probable membrane protein Rv1733c/MT1774 (Rv1733c, MT1774) (Catalog #AAA1030677) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-210. The amino acid sequence is listed below: MIATTRDREG ATMITFRLRL PCRTILRVFS RNPLVRGTDR LEAVVMLLAV TVSLLTIPFA AAAGTAVQDS RSHVYAHQAQ TRHPATATVI DHEGVIDSNT TATSAPPRTK ITVPARWVVN GIERSGEVNA KPGTKSGDRV GIWVDSAGQL VDEPAPPARA IADAALAALG LWLSVAAVAG ALLALTRAIL IRVRNASWQH DIDSLFCTQR. It is sometimes possible for the material contained within the vial of "Probable membrane protein Rv1733c/MT1774 (Rv1733c, MT1774), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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