Probable histone-arginine methyltransferase 1.4 (PRMT14) Recombinant Protein | PRMT14 recombinant protein

Recombinant Arabidopsis thaliana Probable histone-arginine methyltransferase 1.4 (PRMT14) , partial

• Gene Names: PRMT4A; ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 4A; ATPRMT4A; K19E20.17; K19E20_17; protein arginine methyltransferase 4A
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable histone-arginine methyltransferase 1.4 (PRMT14); Recombinant Arabidopsis thaliana Probable histone-arginine methyltransferase 1.4 (PRMT14); partial; PRMT14 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 526

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 30695591
• NCBI GeneID: 834961
• NCBI Accession #: NP_199713.2
• NCBI GenBank Nucleotide #: NM_124279.5
• UniProt Accession #: A3KPF2; Q3E8E0; Q84WN5; Q9FI68
• Molecular Weight: 58,713 Da
• NCBI Official Full Name: protein arginine methyltransferase 4A
• NCBI Official Symbol: PRMT4A
• NCBI Official Synonym Symbols: ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 4A; ATPRMT4A; K19E20.17; K19E20_17; protein arginine methyltransferase 4A
• NCBI Protein Information: protein arginine methyltransferase 4A
• UniProt Protein Name: Probable histone-arginine methyltransferase 1.4
• Protein Family: Probable histone-arginine methyltransferase
• UniProt Gene Name: PRMT14
• UniProt Synonym Gene Names: CARM1B; PRMT4A; AtPRMT14; AtPRMT4A

NCBI Description

Encodes a type I protein arginine methyltransferase. PRMT4a can catalyze the asymmetric dimethylation of arginines 2,17, and 26 on histone 3 and can also methylate myelin basic protein in vitro. Double mutants lacking PRMT4a and 4b have reduced levels of histone 3 methylated at R17. These double mutants flower late due to defects in the autonomous pathway and they have elevated levels of FLC transcripts.

Uniprot Description

Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation, methylates histone H3 and activates transcription via chromatin remodeling.