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Prolactin Receptor Recombinant Protein | PRLR recombinant protein

Recombinant Mouse Prolactin Receptor Protein

Gene Names
Prlr; Pr-1; Pr-3; AI987712; Prlr-rs1
Applications
ELISA, Western Blot, SDS-Page
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
Prolactin Receptor; Recombinant Mouse Prolactin Receptor Protein; Prolactin receptor; PRL-R; PRLR recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.
Sequence
QSPPGKPEIH KCRSPDKETF TCWWNPGSDG GLPTNYSLTY SKEGEKNTYE CPDYKTSGPN SCFFSKQYTS IWKIYIITVN ATNEMGSSTS DPLYVDVTYI VEPEPPRNLT LEVKQLKDKK TYLWVKWLPP TITDVKTGWF TMEYEIRLKS EEADEWEIHF TGHQTQFKVF DLYPGQKYLV QTRCKPDHGY WSRWGQEKSI EIPNDFTLKD VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
Sequence Length
303
Applicable Applications for PRLR recombinant protein
ELISA (EIA), Western Blot (WB), SDS-PAGE
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for PRLR recombinant protein
Recombinant Mouse Prolactin Receptor Protein is produced by mammalian expression system and the target gene encoding Gln20-Asp229 is expressed with a Fc tag at the C-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
prolactin receptor isoform 3
NCBI Official Synonym Full Names
prolactin receptor
NCBI Official Symbol
Prlr
NCBI Official Synonym Symbols
Pr-1; Pr-3; AI987712; Prlr-rs1
NCBI Protein Information
prolactin receptor
UniProt Protein Name
Prolactin receptor
Protein Family
UniProt Gene Name
Prlr
UniProt Synonym Gene Names
PRL-R
UniProt Entry Name
PRLR_MOUSE

Uniprot Description

PRLR: receptor for the anterior pituitary hormone prolactin and placental lactogen I and II. Interacts with Cyclophilin A, differentially regulating various signaling pathways from the PrlR. Prolactin signaling is attenuated by threonine and tyrosine phosphorylation. Two alternative splice isoforms have been identified.

Protein type: Receptor, cytokine; Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; intracellular

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; peptide hormone binding; metal ion binding; protein kinase binding; prolactin receptor activity

Biological Process: regulation of cell adhesion; lactation; transmembrane receptor protein tyrosine kinase activation (dimerization); regulation of epithelial cell differentiation; JAK-STAT cascade

Research Articles on PRLR

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Product Notes

The PRLR prlr (Catalog #AAA8305320) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Prolactin Receptor can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), SDS-PAGE. Researchers should empirically determine the suitability of the PRLR prlr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QSPPGKPEIH KCRSPDKETF TCWWNPGSDG GLPTNYSLTY SKEGEKNTYE CPDYKTSGPN SCFFSKQYTS IWKIYIITVN ATNEMGSSTS DPLYVDVTYI VEPEPPRNLT LEVKQLKDKK TYLWVKWLPP TITDVKTGWF TMEYEIRLKS EEADEWEIHF TGHQTQFKVF DLYPGQKYLV QTRCKPDHGY WSRWGQEKSI EIPNDFTLKD VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K. It is sometimes possible for the material contained within the vial of "Prolactin Receptor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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