Pregnancy-Associated Plasma Protein A Fragment Recombinant Protein | Pappa2 recombinant protein
Pregnancy-Associated Plasma Protein A Fragment, Recombinant, Human
Gene Names
Pappa2; PLAC3; Pappe; PAPP-A2
Applications
ELISA
Purity
Highly Purified95% by SDS-PAGE.
Synonyms
Pregnancy-Associated Plasma Protein A Fragment; Recombinant; Human; Pappa2 recombinant protein
Host
Human, Recombinant, E Coli
Purity/Purification
Highly Purified
95% by SDS-PAGE.
95% by SDS-PAGE.
Form/Format
Supplied as a liquid.
Applicable Applications for Pappa2 recombinant protein
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA., , Recommended Dilution:, Optimal dilutions to be determined by the researcher.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Pappa2 recombinant protein
Recombinant PAPP-A comprises a 191 amino acid fragment (81-271) corresponding to the PAPP-A 'Jelly-Roll' domain fragment and is expressed in E. coli with an amino- terminal hexahistidine tag.
PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems.
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500kD, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
PAPP-A is a large zinc binding protein, which acts as a metalloprotease and has been shown to cleave insulin-like growth factor binding protein-4. PAPP-A can act as a regulator of IGF bioactivity in several biological systems, including the human ovary and cardiovascular systems.
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500kD, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
Product Categories/Family for Pappa2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
pappalysin 2
NCBI Official Synonym Full Names
pappalysin 2
NCBI Official Symbol
Pappa2
NCBI Official Synonym Symbols
PLAC3; Pappe; PAPP-A2
NCBI Protein Information
pappalysin 2; placenta-specific 3; pregnancy-associated plasma protein-E; pregnancy-associated plasma preproprotein-A2
Protein Family
Research Articles on Pappa2
Similar Products
Product Notes
The Pappa2 (Catalog #AAA637079) is a Recombinant Protein produced from Human, Recombinant, E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Pregnancy-Associated Plasma Protein A Fragment can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA.,, Recommended Dilution:, Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Pappa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pregnancy-Associated Plasma Protein A Fragment, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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