Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a) Recombinant Protein | Ppp1r15a recombinant protein
Recombinant Mouse Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
Gene Names
Ppp1r15a; Gadd34; Myd116; 9630030H21
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a); Recombinant Mouse Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a); Ppp1r15a recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
40-657aa; Partial
Sequence
EVPEAWLAKTVTGADQIEAAALLTPTPVSGNLLPHGETEESGSPEQSQAAQRLCLVEAESSPPETWGLSNVDEYNAKPGQDDLREKEMERTAGKATLQPAGLQGADKRLGEVVAREEGVAEPAYPTSQLEGGPAENEEDGETVKTYQASAASIAPGYKPSTPVPFLGEAEHQATEEKGTENKADPSNSPSSGSHSRAWEYYSREKPKQEGEAKVEAHRAGQGHPCRNAEAEEGGPETTFVCTGNAFLKAWVYRPGEDTEEEDNSDSDSAEEDTAQTGATPHTSAFLKAWVYRPGEDTEEEDSDSDSAEEDTAQTGATPHTSAFLKAWVYRPGEDTEEENSDLDSAEEDTAQTGATPHTSAFLKAWVYRPGEDTEEENSDLDSAEEDTAQTGATPHTSPFLKAWVYRPGEDTEDDTEEEEDSENVAPGDSETADSSQSPCLQPQRCLPGEKTKGRGEEPPLFQVAFYLPGEKPESPWAAPKLPLRLQRRLRLFKAPTRDQDPEIPLKARKVHFAEKVTVHFLAVWAGPAQAARRGPWEQFARDRSRFARRIAQAEEKLGPYLTPDSRARAWARLRNPSLPQSEPRSSSEATPLTQDVTTPSPLPSETPSPSLYLGGRRG
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Ppp1r15a recombinant protein
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,474 Da
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 15A
NCBI Official Synonym Full Names
protein phosphatase 1, regulatory (inhibitor) subunit 15A
NCBI Official Symbol
Ppp1r15a
NCBI Official Synonym Symbols
Gadd34; Myd116; 9630030H21
NCBI Protein Information
protein phosphatase 1 regulatory subunit 15A
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 15A
Protein Family
UniProt Gene Name
Ppp1r15a
UniProt Synonym Gene Names
Gadd34; Myd116
Uniprot Description
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. In case of infection with vesicular stomatitis virus (VSV), impairs viral replication.
Research Articles on Ppp1r15a
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Product Notes
The Ppp1r15a ppp1r15a (Catalog #AAA963288) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 40-657aa; Partial. The amino acid sequence is listed below: EVPEAWLAKT VTGADQIEAA ALLTPTPVSG NLLPHGETEE SGSPEQSQAA QRLCLVEAES SPPETWGLSN VDEYNAKPGQ DDLREKEMER TAGKATLQPA GLQGADKRLG EVVAREEGVA EPAYPTSQLE GGPAENEEDG ETVKTYQASA ASIAPGYKPS TPVPFLGEAE HQATEEKGTE NKADPSNSPS SGSHSRAWEY YSREKPKQEG EAKVEAHRAG QGHPCRNAEA EEGGPETTFV CTGNAFLKAW VYRPGEDTEE EDNSDSDSAE EDTAQTGATP HTSAFLKAWV YRPGEDTEEE DSDSDSAEED TAQTGATPHT SAFLKAWVYR PGEDTEEENS DLDSAEEDTA QTGATPHTSA FLKAWVYRPG EDTEEENSDL DSAEEDTAQT GATPHTSPFL KAWVYRPGED TEDDTEEEED SENVAPGDSE TADSSQSPCL QPQRCLPGEK TKGRGEEPPL FQVAFYLPGE KPESPWAAPK LPLRLQRRLR LFKAPTRDQD PEIPLKARKV HFAEKVTVHF LAVWAGPAQA ARRGPWEQFA RDRSRFARRI AQAEEKLGPY LTPDSRARAW ARLRNPSLPQ SEPRSSSEAT PLTQDVTTPS PLPSETPSPS LYLGGRRG . It is sometimes possible for the material contained within the vial of "Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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