TOMM7 positive control
TOMM7 Positive Control
Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]
Uniprot Description
TOMM7: Required for assembly and stability of the TOM complex. Belongs to the Tom7 family.
Protein type: Membrane protein, integral; Mitochondrial
Chromosomal Location of Human Ortholog: 7p15.3
Cellular Component: integral to mitochondrial outer membrane; mitochondrial outer membrane; mitochondrial outer membrane translocase complex; mitochondrion
Molecular Function: protein binding; protein channel activity; protein transmembrane transporter activity
Biological Process: macroautophagy; protein import into mitochondrial matrix; protein import into mitochondrial outer membrane; protein targeting to mitochondrion; regulation of protein stability
Research Articles on TOMM7
Similar Products
Product Notes
The TOMM7 tomm7 (Catalog #AAA543339) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TOMM7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500. Researchers should empirically determine the suitability of the TOMM7 tomm7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TOMM7, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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