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IFI27 positive control

IFI27 Positive Control

Gene Names
IFI27; P27; ISG12; FAM14D; ISG12A
Applications
Western Blot
Synonyms
IFI27; IFI27 Positive Control; 2310061N23Rik; FAM14D; IFI 27; Interferon alpha induced 11.5 kDa protein; Interferon inducible protein 27; interferon-stimulated gene 12; ISG 12; ISG12A; P27 antibody; IFI27 positive control
Ordering
For Research Use Only!
Form/Format
Western Blot Positive Control
Sequence Length
119
Applicable Applications for IFI27 positive control
Western Blot (WB)
Application Notes
Western Blot: 1:500
Immunogen
Purified Protein
Expression
Up-regulated by interferons
Molecular Function
Lamin binding; RNA polymerase II activating transcription factor binding
Structure
Belongs to the IFI6/IFI27 family.
Subcellular Location
Mitochondrion; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for IFI27 positive control
Western Blot Positive Control Interferon, alpha-inducible protein 27
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,268 Da
NCBI Official Full Name
interferon alpha-inducible protein 27, mitochondrial isoform 2
NCBI Official Synonym Full Names
interferon alpha inducible protein 27
NCBI Official Symbol
IFI27
NCBI Official Synonym Symbols
P27; ISG12; FAM14D; ISG12A
NCBI Protein Information
interferon alpha-inducible protein 27, mitochondrial
UniProt Protein Name
Interferon alpha-inducible protein 27, mitochondrial
UniProt Gene Name
IFI27
UniProt Synonym Gene Names
p27; ISG12(a)
UniProt Entry Name
IFI27_HUMAN

Uniprot Description

IFI27: Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Belongs to the IFI6/IFI27 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion; nuclear inner membrane

Molecular Function: lamin binding

Biological Process: caspase activation; negative regulation of transcription from RNA polymerase II promoter; regulation of protein export from nucleus

Research Articles on IFI27

Similar Products

Product Notes

The IFI27 ifi27 (Catalog #AAA542861) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IFI27 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500. Researchers should empirically determine the suitability of the IFI27 ifi27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFI27, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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