Mucin Native Protein | MUC native protein
Mucin-Porcine
Gene Names
MUC2; MLP; SMUC; MUC-2
Purity
Partially Purified
Synonyms
Mucin; Mucin-Porcine; Purified Native Porcine Mucin Protein; MUC protein; MUC native protein
Host
Porcine stomach
Purity/Purification
Partially Purified
Form/Format
Faint yellow powder.
Concentration
10 grams, Lyophilized (varies by lot)
Solubility
5mg/ml, 0.1M acetate, pH 5.0%
% Bound as N-Acetylneuraminic Acid: 0.8%
% Free N-Acetylneuraminic: 0.1%
% Bound as N-Acetylneuraminic Acid: 0.8%
% Free N-Acetylneuraminic: 0.1%
Biohazard
For research use only. Use standard laboratory precautions when handling.
Protein Type
Native
Biological Significance
Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. Mucins' key characteristic is their ability to form gels; therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. They often take an inhibitory role. Some mucins are associated with controlling mineralization, including nacre formation in molluscs, calcification in echinoderms and bone formation in vertebrates. They bind to pathogens as part of the immune system. Overexpression of the mucin proteins, especially MUC1 is associated with many types of cancer.
Preparation and Storage
Ships ambient or refrigerated. Upon receipt store at 4°C.
Related Product Information for MUC native protein
Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. Mucins' key characteristic is their ability to form gels; therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. They often take an inhibitory role. Some mucins are associated with controlling mineralization, including nacre formation in molluscs, calcification in echinoderms and bone formation in vertebrates. They bind to pathogens as part of the immune system. Overexpression of the mucin proteins, especially MUC1 is associated with many types of cancer.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
Research Articles on MUC
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Product Notes
The MUC (Catalog #AAA5311023) is a Native Protein produced from Porcine stomach and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Mucin, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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