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Diamine Oxidase, Porcine Kidney Enzyme | DAO1 enzyme

Diamine Oxidase, Porcine Kidney (Amine:oxygen oxidoreductase, deaminating, pyridoxal-containing)

Gene Names
DAO1; DAO; DAAO; DAMOX
Purity
Purified
Synonyms
Diamine Oxidase; Porcine Kidney; Porcine Kidney (Amine:oxygen oxidoreductase; deaminating; pyridoxal-containing); DAO1 enzyme
Ordering
For Research Use Only!
Host
Porcine kidney
Purity/Purification
Purified
CAS Number
9001-53-0
Unit Definition
One unit will oxidize 1umole of putrescine per hr at pH 7.2 at 37 degree C.

Activity: 0.05 unit/mg solid
Preparation and Storage
-20 degree C
Related Product Information for DAO1 enzyme
Diamine oxidase (DAO) is a flavoprotein/enzyme which catalyzes the aerobic oxidation of amines to the corresponding aldehyde and ammonia. Diamine oxidase is synthesized primarily in the gastrointestinal mucosal cells. Serum levels of DAO have been used as an indicator of the integrity and/or functional mass of the intestinal mucosa. The enzyme is also produced by the placenta and is elevated in newborn serum.
Product Categories/Family for DAO1 enzyme

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,336 Da
NCBI Official Full Name
D-amino-acid oxidase
NCBI Official Symbol
DAO1
NCBI Official Synonym Symbols
DAO; DAAO; DAMOX
NCBI Protein Information
D-amino-acid oxidase
UniProt Protein Name
D-amino-acid oxidase
UniProt Gene Name
DAO
UniProt Synonym Gene Names
DAAO; DAMOX; DAO
UniProt Entry Name
OXDA_PIG

Uniprot Description

Function: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.

Catalytic activity: A D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + H2O2. Ref.6 Ref.7 Ref.9

Cofactor: FAD. Ref.6

Subunit structure: Homodimer. Ref.12

Subcellular location: Peroxisome.

Sequence similarities: Belongs to the DAMOX/DASOX family.

Research Articles on DAO1

Similar Products

Product Notes

The DAO1 dao (Catalog #AAA653980) is an Enzyme produced from Porcine kidney and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Diamine Oxidase, Porcine Kidney, Enzyme" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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