Diamine Oxidase, Porcine Kidney Enzyme | DAO1 enzyme
Diamine Oxidase, Porcine Kidney (Amine:oxygen oxidoreductase, deaminating, pyridoxal-containing)
Activity: 0.05 unit/mg solid
NCBI and Uniprot Product Information
Uniprot Description
Function: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Catalytic activity: A D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + H2O2. Ref.6 Ref.7 Ref.9
Cofactor: FAD. Ref.6
Subunit structure: Homodimer. Ref.12
Subcellular location: Peroxisome.
Sequence similarities: Belongs to the DAMOX/DASOX family.
Research Articles on DAO1
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Product Notes
The DAO1 dao (Catalog #AAA653980) is an Enzyme produced from Porcine kidney and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Diamine Oxidase, Porcine Kidney, Enzyme" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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