Porcine Ubiquitin Conjugation Factor E4 A (UBE4A) ELISA Kit | UBE4A elisa kit
Porcine Ubiquitin Conjugation Factor E4 A (UBE4A) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Uniprot Description
UBE4A: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. Belongs to the ubiquitin conjugation factor E4 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: ER-associated protein catabolic process; protein polyubiquitination; ubiquitin-dependent protein catabolic process
Research Articles on UBE4A
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Product Notes
The Porcine UBE4A ube4a (Catalog #AAA9391430) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9391430 ELISA Kit recognizes Porcine UBE4A. It is sometimes possible for the material contained within the vial of "Ubiquitin Conjugation Factor E4 A (UBE4A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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