Porcine Chromatin assembly factor 1 subunit B (CHAF1B) ELISA Kit | CHAF1B elisa kit
Porcine Chromatin assembly factor 1 subunit B (CHAF1B) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008]
Uniprot Description
CAF-1B: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex. Belongs to the WD repeat HIR1 family.
Protein type: DNA replication
Chromosomal Location of Human Ortholog: 21q22.13
Cellular Component: nucleoplasm; protein complex; nuclear chromatin; cytoplasm; nucleus; cytosol
Molecular Function: histone binding; unfolded protein binding; chromatin binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; chromatin assembly; protein complex assembly; cell cycle; DNA repair; DNA replication; reproduction; DNA replication-dependent nucleosome assembly
Research Articles on CHAF1B
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Product Notes
The Porcine CHAF1B chaf1b (Catalog #AAA7224247) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7224247 ELISA Kit recognizes Porcine CHAF1B. It is sometimes possible for the material contained within the vial of "Chromatin assembly factor 1 subunit B (CHAF1B), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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