Porcine CAP-Gly domain-containing linker protein 1 (CLIP1) ELISA Kit | CLIP1 elisa kit

Porcine CAP-Gly domain-containing linker protein 1 (CLIP1) ELISA Kit

Gene Names

CLIP1; RSN; CLIP; CYLN1; CLIP170; CLIP-170

Reactivity

Porcine

Synonyms

CAP-Gly domain-containing linker protein 1 (CLIP1); Porcine CAP-Gly domain-containing linker protein 1 (CLIP1) ELISA Kit; CLIP1 elisa kit

Ordering
Cat. Num. AAA7209797 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Porcine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Preparation and Storage

Store all reagents at 2-8 degree C.

Product Categories/Family for CLIP1 elisa kit

Cancer

NCBI and Uniprot Product Information

NCBI GI #

261260059

NCBI GeneID

6249

Molecular Weight

156,781 Da

NCBI Official Full Name

CAP-Gly domain-containing linker protein 1

NCBI Official Synonym Full Names

CAP-GLY domain containing linker protein 1

NCBI Official Symbol

CLIP1

NCBI Official Synonym Symbols

RSN; CLIP; CYLN1; CLIP170; CLIP-170

NCBI Protein Information

CAP-Gly domain-containing linker protein 1; cytoplasmic linker protein 1; cytoplasmic linker protein CLIP-170; cytoplasmic linker protein 170 alpha-2; restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)

UniProt Protein Name

CAP-Gly domain-containing linker protein 1

Protein Family

CAP-Gly domain-containing linker protein

UniProt Gene Name

CLIP1

UniProt Synonym Gene Names

CYLN1; RSN; CLIP-170

UniProt Entry Name

CLIP1_HUMAN

NCBI Description

The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

Restin: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. Interacts with MTOR; phosphorylates and regulates CLIP1. Interacts (via CAP-Gly domains) with tubulin. Interacts with SLAIN2. Interacts (via zinc finger) with DCTN1. Interacts with MAPRE1 and MAPRE3. Detected in dendritic cells. Highly expressed in the Reed-Sternberg cells of Hodgkin disease. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q24.3

Cellular Component: kinetochore; microtubule cytoskeleton; ruffle; centrosome; microtubule; cytoplasmic vesicle membrane; cytoplasmic microtubule; cytoplasm; intermediate filament; cytosol; endosome

Molecular Function: tubulin binding; microtubule plus-end binding; protein binding; protein homodimerization activity; nucleic acid binding; zinc ion binding; microtubule binding; metal ion binding

Biological Process: mitosis; positive regulation of microtubule polymerization; mitotic cell cycle; microtubule bundle formation

Research Articles on CLIP1

1. Depletion of CLIP-170 significantly impaired vascular endothelial tube formation and sprouting in vitro and inhibited breast tumor growth in mice by decreasing tumor vascularization.

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Product Notes

The Porcine CLIP1 clip1 (Catalog #AAA7209797) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7209797 ELISA Kit recognizes Porcine CLIP1. It is sometimes possible for the material contained within the vial of "CAP-Gly domain-containing linker protein 1 (CLIP1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Porcine CAP-Gly domain-containing linker protein 1 (CLIP1) ELISA Kit | CLIP1 elisa kit