Porcine ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3) ELISA Kit | ARFGAP3 elisa kit
Porcine ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
Uniprot Description
ARF GAP 3: GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Protein type: GAPs; GAPs, ARF
Chromosomal Location of Human Ortholog: 22q13.2
Cellular Component: Golgi membrane; Golgi apparatus; membrane; cytoplasm; cytosol
Molecular Function: protein binding; zinc ion binding; protein transporter activity
Biological Process: vesicle-mediated transport; intracellular protein transport; protein secretion; positive regulation of GTPase activity
Research Articles on ARFGAP3
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Product Notes
The Porcine ARFGAP3 arfgap3 (Catalog #AAA7243978) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7243978 ELISA Kit recognizes Porcine ARFGAP3. It is sometimes possible for the material contained within the vial of "ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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