Popeye domain-containing protein 2 (Popdc2) Recombinant Protein | Popdc2 recombinant protein
Recombinant Mouse Popeye domain-containing protein 2 (Popdc2)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Popeye domain containing family of membrane proteins. Proteins of this family contain three helical transmembrane domains and a conserved intracellular Popeye domain. In the adult mouse, this gene is expressed at high levels in cardiac myocytes, and mice deficient for this gene develop stress-induced cardiac pacemaker dysfunction. The protein binds to a two-pore domain potassium channel and recruits it to the plasma membrane. Cyclic adenosine monophosphate negatively regulates this interaction through the Popeye domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Uniprot Description
POPDC2: May play an important role in heart development. Belongs to the popeye family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: integral to membrane; membrane; plasma membrane; sarcolemma
Molecular Function: cAMP binding
Biological Process: regulation of heart rate; regulation of membrane potential
Research Articles on Popdc2
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Product Notes
The Popdc2 popdc2 (Catalog #AAA7026843) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-367aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Popdc2 popdc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MSANGSSVAQ LLWQPPVCRS WKPDVEGAVY HLANCFLLMG FMAGSGVYGC FYLFGILGPG YLCCVLWGWF DACGLDIVLW NVLLTVACLL QLAQLVYRVR VNTLPEEFNL LYRTLCLPLQ VPLQVYKEIV HCCHEQVLTL ATEQTYAVEG ETPINRLSLL LSGRVRVSQD GQFLHYIFPY QFMDSPEWES LHPSEEGTFQ VTLTAETECS YISWPRKNLY LLLNRERYIS RLFSALLGYD ISEKLYTLND KLFAKFGLRF DIRLPSLYHV LSPSASDGEP ESEKDDEEAL EAAVSPAQAR PICIVPTPPC SAPPATTNFP VPLPRARMPR MPRPDSGNLA SRRPLQNSSQ VMSRSQAPLA PIHTPEL. It is sometimes possible for the material contained within the vial of "Popeye domain-containing protein 2 (Popdc2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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