Western Blot (WB)
(Western blot (WB) analysis of ZNT8 polyclonal antibody at 1:500 dilutionLaneA: H9C2 whole cell lysateLaneB: K562 whole cell lysate)
Rabbit anti-Human, Rat ZNT8 Polyclonal Antibody | anti-ZNT8 antibody
ZNT8 polyclonal antibody
Gene Names
SLC30A8; ZNT8; ZnT-8
Reactivity
Human, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
Synonyms
ZNT8; Polyclonal Antibody; ZNT8 polyclonal antibody; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8; SLC30A8; anti-ZNT8 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
ZNT8 polyclonal antibody detects endogenous levels of ZNT8 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-ZNT8 antibody
Western Blot (WB)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:200
IHC: 1:50~1:200
Immunogen
Synthetic peptide, corresponding to Human ZNT8
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Western Blot (WB)
(Western blot (WB) analysis of ZNT8 polyclonal antibody at 1:500 dilutionLaneA: H9C2 whole cell lysateLaneB: K562 whole cell lysate)
Western Blot (WB)
(Western blot (WB) analysis of ZNT8 polyclonal antibody at 1:500 dilutionLaneA: H9C2 whole cell lysateLaneB: K562 whole cell lysate)
Related Product Information for anti-ZNT8 antibody
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions (such as neuroregulation) and acts as a cofactor for numerous enzymes and transcription factors. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members commonly contain six membrane-spanning domains, a large histidine-rich intracellular loop and a C-terminal tail. ZnT-8 (zinc transporter 8), also known as SLC30A8 (solute carrier family 30 member 8), is a 369 amino acid multi-pass membrane protein that belongs to the ZnT family and is a major autoantigen in type I diabetes. Expressed specifically in pancreas islet cells, ZnT-8 functions as a zinc-efflux transporter that facilitates the accumulation of zinc in intracellular vesicles and is essential for the zinc-dependent maturation of Insulin within pancreatic cells. Multiple isoforms of ZnT-8 exist due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,755 Da
NCBI Official Full Name
zinc transporter 8 isoform a
NCBI Official Synonym Full Names
solute carrier family 30 (zinc transporter), member 8
NCBI Official Symbol
SLC30A8
NCBI Official Synonym Symbols
ZNT8; ZnT-8
NCBI Protein Information
zinc transporter 8; zinc transporter ZnT-8
UniProt Protein Name
Zinc transporter 8
UniProt Gene Name
SLC30A8
UniProt Synonym Gene Names
ZNT8; ZnT-8
UniProt Entry Name
ZNT8_HUMAN
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Product Notes
The ZNT8 slc30a8 (Catalog #AAA3014938) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNT8 polyclonal antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZNT8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500~1:1000 IHC: 1:50~1:200. Researchers should empirically determine the suitability of the ZNT8 slc30a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNT8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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