Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7605982 (SLC30A7 antibody) at dilution of 1:100)
Rabbit ZnT7 Polyclonal Antibody | anti-ZnT7 antibody
ZnT7 Rabbit Polyclonal
Purification: Immunogen Affinity Purified
Purification: Immunogen Affinity Purified
Immunohistochemistry (IHC) 1:20-200
Immunoflourescence (IF)1:20-200
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7605982 (SLC30A7 antibody) at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7605982 (SLC30A7 antibody) at dilution of 1:100)
Western Blot (WB)
(mouse lung tissue were subjected to SDS PAGE followed by western blot with MBS7605982 (SLC30A7 antibody) at dilution of 1:1000)
Western Blot (WB)
(mouse lung tissue were subjected to SDS PAGE followed by western blot with MBS7605982 (SLC30A7 antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]
Uniprot Description
SLC30A7: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Vesicle; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 1p21.2
Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; Golgi apparatus; integral to membrane; membrane; perinuclear region of cytoplasm; vesicle
Molecular Function: zinc ion transmembrane transporter activity
Biological Process: response to zinc ion; sequestering of zinc ion
Research Articles on ZnT7
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Product Notes
The ZnT7 slc30a7 (Catalog #AAA7605982) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZnT7 Rabbit Polyclonal reacts with Human, Mouse, Rat. Other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's ZnT7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western Blot (WB) 1:200-1:2000 Immunohistochemistry (IHC) 1:20-200 Immunoflourescence (IF)1:20-200. Researchers should empirically determine the suitability of the ZnT7 slc30a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZnT7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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