Western Blot (WB)
(Western Blot analysis of ZNRD1 expression in transfected 293T cell line by ZNRD1 polyclonal antibody. Lane 1: ZNRD1 transfected lysate (13.9kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human ZNRD1 Polyclonal Antibody | anti-ZNRD1 antibody
ZNRD1 (DNA-directed RNA Polymerase I Subunit RPA12, Zinc Ribbon Domain-containing Protein 1, RPA12, MGC13376) (HRP)
Western Blot (WB)
(Western Blot analysis of ZNRD1 expression in transfected 293T cell line by ZNRD1 polyclonal antibody. Lane 1: ZNRD1 transfected lysate (13.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of ZNRD1 expression in transfected 293T cell line by ZNRD1 polyclonal antibody. Lane 1: ZNRD1 transfected lysate (13.9kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
ZNRD1: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Protein type: Nucleolus; Transcription initiation complex; Transferase
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: nucleoplasm; DNA-directed RNA polymerase I complex
Molecular Function: nucleic acid binding; zinc ion binding
Biological Process: negative regulation of gene expression, epigenetic; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; transcription from RNA polymerase I promoter; RNA elongation from RNA polymerase I promoter; gene expression; transcription initiation from RNA polymerase I promoter; termination of RNA polymerase I transcription; regulation of gene expression, epigenetic
Research Articles on ZNRD1
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Product Notes
The ZNRD1 znrd1 (Catalog #AAA6399309) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNRD1 (DNA-directed RNA Polymerase I Subunit RPA12, Zinc Ribbon Domain-containing Protein 1, RPA12, MGC13376) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZNRD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ZNRD1 znrd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNRD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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