Rabbit anti-Human ZNF541 Polyclonal Antibody | anti-ZNF541 antibody

ZNF541 Polyclonal Antibody

Cat. Num. AAA3007446

• Reactivity: Human
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
• Synonyms: ZNF541; Polyclonal Antibody; ZNF541 Polyclonal Antibody; Zinc finger protein 541; anti-ZNF541 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ZNF541 polyclonal antibody detects endogenous levels of ZNF541 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 1346

• Applicable Applications for anti-ZNF541 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 361-405 of Human ZNF541
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of ZNF541 polyclonal antibody at 1:500 dilutionLane1:L02 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:SK-OVCAR3 whole cell lysate (40ug))

Related Product Information for anti-ZNF541 antibody

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF541 (zinc finger protein 541) is a 1, 365 amino acid nuclear protein that acts as a component of a chromatin remodeling multiprotein complex involved in spermatogenesis. Existing as three alternatively spliced isoforms, ZNF541 interacts with both HSPA2 and HDAC1, and contains one SANT domain, a ELM2 domain and five C2H2-type zinc fingers. The gene encoding ZNF541 maps to human chromosome 19q13.33. Chromosome 19 consists of over 63 million bases, houses approximately 1, 400 genes and is the genetic home for a number of immunoglobulin (Ig) superfamily members, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

NCBI and Uniprot Product Information

• NCBI GI #: 459215033
• NCBI Accession #: NP_001264004.1
• NCBI GenBank Nucleotide #: NP_001264004.1
• UniProt Accession #: Q9H0D2
• Molecular Weight: ~ 160kDa
• NCBI Official Full Name: zinc finger protein 541
• UniProt Protein Name: Zinc finger protein 541
• Protein Family: Zinc finger protein
• UniProt Gene Name: ZNF541
• UniProt Entry Name: ZN541_HUMAN

Uniprot Description

ZNF541: Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding; chromatin binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; spermatogenesis; cell differentiation