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Western Blot (WB) (ZNF346 rabbit polyclonal antibody. Western Blot analysis of ZNF346 expression in human pancreas.)

Rabbit anti-Human, Mouse ZNF346 Polyclonal Antibody | anti-ZNF346 antibody

ZNF346 (Zinc Finger Protein 346, Zfp346, Just Another Zinc Finger Protein, JAZ) (HRP)

Gene Names
ZNF346; JAZ; Zfp346
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ZNF346; Polyclonal Antibody; ZNF346 (Zinc Finger Protein 346; Zfp346; Just Another Zinc Finger Protein; JAZ) (HRP); anti-ZNF346 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ZNF346. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Sequence Length
4314
Applicable Applications for anti-ZNF346 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human ZNF346, aa1-294 (NP_036411.1).
Immunogen Sequence
MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEVEHMIQKNQCLFTNTQCKVCCALLISESQKLAHYQSKKHANKVKRYLAIHGMETLKGETKKLDSDQKSSRSKDKNQCCPICNMTFSSPVVAQSHYLGKTHAKNLKLKQQSTKVEALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ZNF346 rabbit polyclonal antibody. Western Blot analysis of ZNF346 expression in human pancreas.)

Western Blot (WB) (ZNF346 rabbit polyclonal antibody. Western Blot analysis of ZNF346 expression in human pancreas.)

Western Blot (WB)

(ZNF346 rabbit polyclonal antibody. Western Blot analysis of ZNF346 expression in mouse liver.)

Western Blot (WB) (ZNF346 rabbit polyclonal antibody. Western Blot analysis of ZNF346 expression in mouse liver.)

Western Blot (WB)

(Western Blot analysis of ZNF346 expression in transfected 293T cell line by ZNF346 polyclonal antibody. Lane 1: ZNF346 transfected lysate (32.9kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of ZNF346 expression in transfected 293T cell line by ZNF346 polyclonal antibody. Lane 1: ZNF346 transfected lysate (32.9kD). Lane 2: Non-transfected lysate.)
Product Categories/Family for anti-ZNF346 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
Homo sapiens zinc finger protein 346 (ZNF346), transcript variant 1, mRNA
NCBI Official Synonym Full Names
zinc finger protein 346
NCBI Official Symbol
ZNF346
NCBI Official Synonym Symbols
JAZ; Zfp346
NCBI Protein Information
zinc finger protein 346
UniProt Protein Name
Zinc finger protein 346
Protein Family
UniProt Gene Name
ZNF346
UniProt Synonym Gene Names
JAZ
UniProt Entry Name
ZN346_HUMAN

NCBI Description

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Uniprot Description

ZNF346: Binds to dsRNA and DNA. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; enzyme binding; zinc ion binding; double-stranded RNA binding

Biological Process: positive regulation of apoptosis

Research Articles on ZNF346

Similar Products

Product Notes

The ZNF346 znf346 (Catalog #AAA6399177) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF346 (Zinc Finger Protein 346, Zfp346, Just Another Zinc Finger Protein, JAZ) (HRP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF346 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ZNF346 znf346 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF346, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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