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Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZKSCAN3 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))

Rabbit anti-Human ZKSCAN3 Polyclonal Antibody | anti-ZKSCAN3 antibody

ZKSCAN3 Antibody

Gene Names
ZKSCAN3; ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ZKSCAN3; Polyclonal Antibody; ZKSCAN3 Antibody; ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.; anti-ZKSCAN3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total ZKSCAN3 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.7mg/ml (varies by lot)
Sequence Length
538
Applicable Applications for anti-ZKSCAN3 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1: 20-100
Immunogen
Fusion protein of human ZKSCAN3
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZKSCAN3 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ZKSCAN3 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200))
Related Product Information for anti-ZKSCAN3 antibody
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
Product Categories/Family for anti-ZKSCAN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,793 Da
NCBI Official Full Name
zinc finger protein with KRAB and SCAN domains 3 isoform 1
NCBI Official Synonym Full Names
zinc finger with KRAB and SCAN domains 3
NCBI Official Symbol
ZKSCAN3
NCBI Official Synonym Symbols
ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.
NCBI Protein Information
zinc finger protein with KRAB and SCAN domains 3
UniProt Protein Name
Zinc finger protein with KRAB and SCAN domains 3
UniProt Gene Name
ZKSCAN3
UniProt Synonym Gene Names
ZFP47; ZNF306; ZNF309; ZSCAN13; Zf47; Zfp-47
UniProt Entry Name
ZKSC3_HUMAN

Uniprot Description

ZNF306: Acts as a transcriptional regulator. Binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3'. Associates with chromatin at the ITGB4 and VEGF promoters. Activates the transcription of genes associated with colon cancer progression. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: cytoplasm; nucleus

Molecular Function: chromatin binding; DNA binding; protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: lysosome organization and biogenesis; negative regulation of autophagy; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent

Research Articles on ZKSCAN3

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Product Notes

The ZKSCAN3 zkscan3 (Catalog #AAA9416989) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZKSCAN3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZKSCAN3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the ZKSCAN3 zkscan3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZKSCAN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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