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Western Blot (WB) (Western blot analysis on NCCIT cell lysates using anti-ZFX rabbit polyclonal antibodies.)

Rabbit anti-Human, Mouse ZFX Polyclonal Antibody | anti-ZFX antibody

ZFX Antibody

Gene Names
ZFX; ZNF926
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Peptide affinity purified
Synonyms
ZFX; Polyclonal Antibody; ZFX Antibody; X-linked zinc finger protein antibody; zfx antibody; ZFX_HUMAN antibody; Zinc finger protein; X-linked antibody; Zinc Finger X Chromosomal Protein antibody; Zinc finger X-chromosomal protein antibody; ZNF926 antibody; anti-ZFX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Peptide affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-ZFX antibody
Western Blot (WB)
Application Notes
WB: 1:2000
Immunogen
Synthetic peptide (KLH-coupled) within human ZFX 360-420 aa.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis on NCCIT cell lysates using anti-ZFX rabbit polyclonal antibodies.)

Western Blot (WB) (Western blot analysis on NCCIT cell lysates using anti-ZFX rabbit polyclonal antibodies.)
Related Product Information for anti-ZFX antibody
The ZFX (X-linked zinc fnger protein) gene is expressed from the inactive X chromosome and is structurally similar to its homologue on the Y chromosome, ZFY. Transcripts of ZFX and ZFY encode proteins composed of a highly acidic amino-terminal domain and a carboxy-terminal zinc-fnger motif that is commonly associated with nucleic acid-binding proteins. Conditional gene targeting studies in mouse have suggested ZFX is also required for self-renewal of embryonic and hematopoietic stem cells. ZFX has also been suggested to play a role in proliferation and expansion of B cells, and could contribute to lymphocyte homeostasis.
Product Categories/Family for anti-ZFX antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
94,386 Da
NCBI Official Full Name
zinc finger X-chromosomal protein isoform 1
NCBI Official Synonym Full Names
zinc finger protein, X-linked
NCBI Official Symbol
ZFX
NCBI Official Synonym Symbols
ZNF926
NCBI Protein Information
zinc finger X-chromosomal protein; X-linked zinc finger protein
UniProt Protein Name
Zinc finger X-chromosomal protein
UniProt Gene Name
ZFX
UniProt Entry Name
ZFX_HUMAN

NCBI Description

This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010]

Uniprot Description

ZFX: Probable transcriptional activator. Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: Xp21.3

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding; transcription coactivator activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on ZFX

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Product Notes

The ZFX zfx (Catalog #AAA9435022) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZFX Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZFX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the ZFX zfx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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