Western Blot (WB)
(Western blot analysis of ZFP36L2 expression in HepG2 (A), HL60 (B) whole cell lysates.)
Rabbit ZFP36L2 Polyclonal Antibody | anti-ZFP36L2 antibody
Anti-ZFP36L2 Antibody
Western Blot (WB)
(Western blot analysis of ZFP36L2 expression in HepG2 (A), HL60 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of ZFP36L2 expression in HepG2 (A), HL60 (B) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of ZFP36L2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of ZFP36L2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq, Jul 2008]
Uniprot Description
ZFP36L2: Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 2p22.3-p21
Cellular Component: cytoplasm; nucleus
Molecular Function: AU-rich element binding; DNA binding; metal ion binding; transcription factor activity
Biological Process: cell proliferation; hemopoiesis; mRNA catabolic process; mRNA catabolic process, deadenylation-dependent decay; regulation of mRNA stability; regulation of transcription, DNA-dependent; somatic stem cell division; somatic stem cell maintenance; T cell differentiation in the thymus
Research Articles on ZFP36L2
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Product Notes
The ZFP36L2 zfp36l2 (Catalog #AAA8242097) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ZFP36L2 Antibody reacts with Human, Mouse, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's ZFP36L2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the ZFP36L2 zfp36l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFP36L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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