Western Blot (WB)
(Host: RabbitTarget Name: ZFP36L1Sample Tissue: Human 293TAntibody Dilution: 1.0ug/ml)
Rabbit ZFP36L1 Polyclonal Antibody | anti-ZFP36L1 antibody
ZFP36L1 antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: ZFP36L1Sample Tissue: Human 293TAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ZFP36L1Sample Tissue: Human 293TAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ZFP36L1Sample Tissue: Human HepG2 Whole CellAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ZFP36L1Sample Tissue: Human HepG2 Whole CellAntibody Dilution: 1ug/ml)
Western Blot (WB)
(WB Suggested Anti-ZFP36L1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that ZFP36L1 is expressed in Jurkat)
Western Blot (WB)
(WB Suggested Anti-ZFP36L1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysateThere is BioGPS gene expression data showing that ZFP36L1 is expressed in Jurkat)
Target Description: ZFP36L1 is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
BRF1: a zinc finger protein that plays an important role in the assembly of the RNA polymerase III initiation factor TFIIIB. Regulates mRNA levels by targeting transcripts containing AREs (AU-rich elements) into the decay pathway. Phosphorylation by Akt apparently generates 14-3-3 binding sites and inhibits BRF1 from promoting mRNA activity.Contains 2 C3H1-type zinc fingers.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 14q22-q24
Cellular Component: nucleus; cytosol
Molecular Function: mRNA binding; protein binding; DNA binding; metal ion binding; transcription factor activity
Biological Process: regulation of translation; neural tube development; cell proliferation; regulation of transcription, DNA-dependent; apoptosis; heart development; multicellular organism growth; T cell differentiation in the thymus; gene expression; regulation of mRNA stability; vasculogenesis; mRNA catabolic process, deadenylation-dependent decay
Research Articles on ZFP36L1
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Product Notes
The ZFP36L1 zfp36l1 (Catalog #AAA3201485) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZFP36L1 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZFP36L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ZFP36L1 zfp36l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GGGFPRRHSV TLPSSKFHQN QLLSSLKGEP APALSSRDSR FRDRSFSEGG. It is sometimes possible for the material contained within the vial of "ZFP36L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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