Rabbit anti-Human ZBED1 Polyclonal Antibody | anti-ZBED1 antibody

ZBED1 Polyclonal Antibody

Cat. Num. AAA2562564

• Gene Names: ZBED1; ALTE; DREF; TRAMP; hDREF
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: ZBED1; Polyclonal Antibody; ZBED1 Polyclonal Antibody; Ac like transposable element; ALTE; BED type zinc finger domain containing protein 1; DNA replication related element binding factor; DREF homolog; HDREF; KIAA0785; Putative Ac like transposon; Putative Ac-like transposable element; TRAMP; Zinc finger BED domain-containing protein 1; Zinc finger BED type containing 1; anti-ZBED1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 0.66mg/mL (varies by lot)
• Sequence Length: 694

• Applicable Applications for anti-ZBED1 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:30-1:150; ELISA: 1:2000-1:5000
• Immunogen: Fusion protein of human ZBED1
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ZBED1 Polyclonal Antibody at dilution of 1:40(×200))

Related Product Information for anti-ZBED1 antibody

This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.

Product Categories/Family for anti-ZBED1 antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 15929151
• NCBI GeneID: 9189
• UniProt Accession #: O96006
• NCBI Official Full Name: ZBED1 protein
• NCBI Official Synonym Full Names: zinc finger BED-type containing 1
• NCBI Official Symbol: ZBED1
• NCBI Official Synonym Symbols: ALTE; DREF; TRAMP; hDREF
• NCBI Protein Information: zinc finger BED domain-containing protein 1
• UniProt Protein Name: Zinc finger BED domain-containing protein 1
• Protein Family: Zinc finger BED domain-containing protein
• UniProt Gene Name: ZBED1
• UniProt Synonym Gene Names: ALTE; DREF; KIAA0785; TRAMP
• UniProt Entry Name: ZBED1_HUMAN

NCBI Description

This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]

Uniprot Description

ZBED1: Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: Xp22.33;Yp11

Cellular Component: nuclear chromosome

Molecular Function: protein dimerization activity; DNA binding; metal ion binding; transposase activity

Biological Process: metabolic process